GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates May be involved in the

May be involved in the control of initiation of DNA replication through its interaction with NAKAP95

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity

The integrin subunit beta 2 plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency

This gene encodes a protein that contains a DNA-binding domain

GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates May be involved in theThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.