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p15 Polyclonal Antibody, 50ul Isothermal Amplification The protein encoded by this

SKU: 86967201859

4.4
SEK185.00 SEK208.00

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p15 Polyclonal Antibody, 50ul Isothermal Amplification The protein encoded by thisCDKN2B lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B encodes a cyclin dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus cyclin dependent kinase inhibitor 2B functions as a cell growth regulator that controls cell cycle G1 progression. The expression of CDKN2B was found to be dramatically

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Description

The protein encoded by this gene| along with its paralog (scaffold attachment factor B1)| is a repressor of estrogen receptor alpha

The protein encoded by this gene belongs to the ETS family of transcription factors

Alternative splicing of this gene results in several transcript variants encoding three different isoforms

This protein is produced predominantly in vascular smooth muscle cells and may play an important role in the regulation of vascular remodeling

p15 Polyclonal Antibody, 50ul Isothermal Amplification The protein encoded by thisCDKN2B lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B encodes a cyclin dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus cyclin dependent kinase inhibitor 2B functions as a cell growth regulator that controls cell cycle G1 progression. The expression of CDKN2B was found to be dramatically

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