MTHFR Polyclonal Antibody, 50ul Custom DNA Oligos The encoded protein has homology

The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32

tumor progression

Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism

Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease

MTHFR Polyclonal Antibody, 50ul Custom DNA Oligos The encoded protein has homologyMethylenetetrahydrofolate reductase encoded by MTHFR catalyzes the conversion of 5,10 methylenetetrahydrofolate to 5 methyltetrahydrofolate, a co substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.