NF-1 Polyclonal Antibody, 100ul Mammalian Expression Reductions in the expression of

Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease

Gene Ontology (GO) annotations related to this gene include chromatin binding and protein complex binding

The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the Catalytic activity is acquired

MOV10L1 is similar to a mouse gene that encodes a putative RNA helicase and shows testis-specific expression

NF-1 Polyclonal Antibody, 100ul Mammalian Expression Reductions in the expression ofNFIA encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene.