ErbB-3 Monoclonal Antibody, 50ul[BT-MCA0503] Organelle Studies The encoded protein is localized

The encoded protein is localized to the endoplasmic reticulum

This proto-oncogene may play a role in the regulation of embryonic development and cell growth

This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway

also known as neur2 or NEURL3

ErbB-3 Monoclonal Antibody, 50ul[BT-MCA0503] Organelle Studies The encoded protein is localizedThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the