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3BP2 Polyclonal Antibody, 20ul Plates & Dishes where it functions as a

SKU: 9021075739

4.8
DKK97.20 DKK130.20

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3BP2 Polyclonal Antibody, 20ul Plates & Dishes where it functions as aThe protein encoded by this gene has an N terminal pleckstrin homology (PH) domain an SH3 binding proline rich region and a C terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T natural killer (NK) and basophilic cells. Mutations in this gene result in cherubism. Multiple

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Description

where it functions as a negative regulator of cell growth and survival

This gene is a member of a gene family which arose through duplication on the X chromosome

It is similar to a rat protein which is a specific partner for the tail domain of myosin V

this enzyme may be the site of mutation in Fanconi anemia

3BP2 Polyclonal Antibody, 20ul Plates & Dishes where it functions as aThe protein encoded by this gene has an N terminal pleckstrin homology (PH) domain an SH3 binding proline rich region and a C terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T natural killer (NK) and basophilic cells. Mutations in this gene result in cherubism. Multiple

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