WDFY1 Polyclonal Antibody, 50ul High Speed Micro-Centrifuges chromosome 10 makes up approximately

chromosome 10 makes up approximately 4

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

In addition| a SNP in this gene is responsible for determination of human earwax type

and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa

WDFY1 Polyclonal Antibody, 50ul High Speed Micro-Centrifuges chromosome 10 makes up approximatelyThe protein encoded by this gene is a phosphatidylinositol 3 phosphate binding protein, which contains a FYVE zinc finger domain and multiple WD 40 repeat domains. When exogenously expressed, it localizes to early endosomes. Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain.