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MEK2 Monoclonal Antibody(7D11), 50ul Erlenmeyer Flasks HNRNPDL (heterogeneous nuclear ribonucleoprotein D

SKU: 92833007684

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SEK185.00 SEK211.00

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MEK2 Monoclonal Antibody(7D11), 50ul Erlenmeyer Flasks HNRNPDL (heterogeneous nuclear ribonucleoprotein DThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1 ERK2 and MAPK2 ERK3. The activation of this kinase itself is dependent on the Ser Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC

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Description

HNRNPDL (heterogeneous nuclear ribonucleoprotein D like) belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs)

|Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine| and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions

Alterations in levels of the encoded protein may be associated with many diseases

Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor

MEK2 Monoclonal Antibody(7D11), 50ul Erlenmeyer Flasks HNRNPDL (heterogeneous nuclear ribonucleoprotein DThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1 ERK2 and MAPK2 ERK3. The activation of this kinase itself is dependent on the Ser Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC

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