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TIG1 Polyclonal Antibody, 100ul Immunoassays which negatively regulates T-cell receptor

SKU: 9308953653

4.5
EUR123.75 EUR165.75

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TIG1 Polyclonal Antibody, 100ul Immunoassays which negatively regulates T-cell receptorThis gene was identified as a retinoid acid (RA) receptor responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.

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Description

which negatively regulates T-cell receptor (TCR) signaling

This gene is expressed mainly in testis with weak expression in the brain

infections and cancer

Mutations in ACVR1B are associated with pituitary tumors

TIG1 Polyclonal Antibody, 100ul Immunoassays which negatively regulates T-cell receptorThis gene was identified as a retinoid acid (RA) receptor responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.

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