PBF Polyclonal Antibody, 50ul Drug Development and Evaluation while defects in this gene

while defects in this gene are associated with multiple types of cancer

This gene is expressed mainly in testis with weak expression in the brain

enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein

PBF Polyclonal Antibody, 50ul Drug Development and Evaluation while defects in this genePTTG1IP (pituitary tumor transforming 1 interacting protein) encodes a single pass type I integral membrane protein, which binds to pituitary tumor transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for PTTG1IP.