UHRF1 Monoclonal Antibody, 100ul Custom Peptide Synthesis Sodium-dependent and pyrimidine-selective

Sodium-dependent and pyrimidine-selective

This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination

where its expression increases in response to a downregulation of microRNAs

a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females

UHRF1 Monoclonal Antibody, 100ul Custom Peptide Synthesis Sodium-dependent and pyrimidine-selectiveThis gene encodes a member of a subfamily of RING finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1 S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53 dependent DNA damage