CaV alpha2delta1 Polyclonal Antibody, 20ul Microbial Genome Editing The protein encoded by RREB1

The protein encoded by RREB1 (ras responsive element binding protein 1) is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter

Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity

the encoded protein may help maintain an open chromatin configuration around transcribable genes

CaV alpha2delta1 Polyclonal Antibody, 20ul Microbial Genome Editing The protein encoded by RREB1The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha 2 and delta subunits of the voltage dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the