FA11 Rabbit Polyclonal Antibody, 20ul[BT-AP09941] Subcellular Fractions |disease:Defects in CHEK2 are associated

|disease:Defects in CHEK2 are associated with Li-Fraumeni syndrome 2 (LFS2)

Associates with the 9-1-1 complex

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by SST

and participate in linking cadherins to intermediate filaments in the cytoskeleton

FA11 Rabbit Polyclonal Antibody, 20ul[BT-AP09941] Subcellular Fractions |disease:Defects in CHEK2 are associatedThis gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains resulting in activated factor XIa a serine protease