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HSP27 Polyclonal Antibody, 50ul[BT-AP04250] Polyclonal Antibody Preparation This gene encodes a protein

SKU: 97319374667

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SEK162.00 SEK185.00

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HSP27 Polyclonal Antibody, 50ul[BT-AP04250] Polyclonal Antibody Preparation This gene encodes a proteinHeat shock protein family B (small) member 1 encoded by HSPB1 is induced by environmental stress and developmental changes. Heat shock protein family B (small) member 1 is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in HSPB1 are a cause of Charcot Marie Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).

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Description

This gene encodes a protein which forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions

The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration

that are linked by disulfide bonds

is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues

HSP27 Polyclonal Antibody, 50ul[BT-AP04250] Polyclonal Antibody Preparation This gene encodes a proteinHeat shock protein family B (small) member 1 encoded by HSPB1 is induced by environmental stress and developmental changes. Heat shock protein family B (small) member 1 is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in HSPB1 are a cause of Charcot Marie Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).

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