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CNGB3 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The N-terminal domain of this

SKU: 98102084065

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CNGB3 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The N-terminal domain of thisThis gene encodes the beta subunit of a cyclic nucleotide gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.

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Description

The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex

This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain

ETS transcription factor is activated by signal-induced phosphorylation

CMTM3 belongs to the chemokine-like factor gene superfamily

CNGB3 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The N-terminal domain of thisThis gene encodes the beta subunit of a cyclic nucleotide gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.

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