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APPL1 Polyclonal Antibody, 100ul Molecular Sciences This gene may also play

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APPL1 Polyclonal Antibody, 100ul Molecular Sciences This gene may also playThe protein encoded by APPL1 has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1) binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD MeCP1 complex. This protein is found associated with

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This gene may also play a role in tumor progression

Certain alleles of this gene are associated with susceptibility to dental caries

and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells

systemic lupus erythematosus and sarcoidosis

APPL1 Polyclonal Antibody, 100ul Molecular Sciences This gene may also playThe protein encoded by APPL1 has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1) binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD MeCP1 complex. This protein is found associated with

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