Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma The PIAS family contains a

The PIAS family contains a conserved RING domain that has been linked to a function as a small ubiquitin-related modifier (SUMO) ligase

An important paralog of this gene is GK

families of heteromeric G proteins

Gene Ontology (GO) annotations related to this gene include death receptor binding

Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma The PIAS family contains aMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.